ABSTRACT
Bachground: The coronavirus disease 2019 (COVID-19) pandemic, which started on February 26, 2020 in city of karachi, spread quickly throughout Pakistan. Material(s) and Method(s): The design of this study was a observational study design and this study was conducted at king Edward medical University Lahore. More than 6,200 persons were afflicted by the illness in the first seven weeks, and there were more than 111 documented fatalities. Many problems arise if we contrast the COVID-19 tragedies in Pakistan with those in nations like China, Iran, and the European Union. The geography of the nation, poverty, poor literacy rates, environmental circumstances, sanitary conditions, and dietary habits are only a few of the difficulties we face in containing this epidemic. Although there are terrible circumstances in each of these areas, Pakistan's COVID-19 epidemic was slower than that of other developing nations. Result(s): The impact of COVID-19 appears to be lessened by Pakistan's humid hot temperature, early reaction to COVID-19, population immune system, BCG vaccination, and the proportion of young individuals. In this essay, we explore the COVID-19 pandemic outbreak in China, Iran, and Pakistan and present its day-to-day changes. We outline the COVID-19 structure and how it compares to SARS-COV and SARS-COV2. The use of Remdesivir (an adenosine analogue used against RNA viruses), Chloroquine (a widely used anti-malarial drug), convalescent plasma, neutralising antibodies targeting the ACE-2 receptor, and an ACE-2-like molecule that might bind to the S protein of the coronavirus are also covered in terms of treatment options and their drawbacks. Also covered are the effects of COVID-19 on Pakistan's economy and government relief measures. Conclusion(s): In conclusion, it may be said that the support systems in place may not be sufficient to stop the spread of the virus. Even with the meagre assistance offered, it is weaker for rural places where the virus's effects may be severe than in the nation's cities. Further research is required as the epidemic develops to better understand governmental efforts to contain the virus and its effects across the nation.Copyright © 2023 Lahore Medical And Dental College. All rights reserved.
ABSTRACT
Aim: To assess the neurological and mental health responses to pandemic Covid-19. Study design: Cohort study Place and duration of study: Department of Medicine, Chandka Medical College Hospital Larkana and Department of Medicine, Khairpur Medical College Hospital Khairpur Mir's from 1st October 2021 to 31st March 2022. Methodology: Two hundred patients who suffered Covid-19 infection and 200 who had any other life event except Covid-19 were enrolled. All patients who were above 18 years of age and were positive for Covid-19 through reverse transcriptase PCR were included in the study.Global Psych trauma Screening was done by enlisting twenty-two items which assessed trauma related symptoms while five items only assessed the factors increasing risks. Result(s): There were 112 (56%) females and 88 (44%) males in Covid-19 patients and 150 (75%) females and 50 (25%) males in non-Covid patients. The mean age of the Covid-19 patients was 49.65+/-15.5 year while of non Covid patients was 39.02+/-12.01 years. A significant increase in post-traumatic stress disorder (PTSD) cases probability was noted in the Covid-19 cases than non Covid-19 related events. Neurological responses showed that patients who had suffered from Covid 19 infections had a generalized weakness with hyposmia formation. Conclusion(s): Covid-19 is related with high level of depression, anxiety, hyposmia and other mental and neurological responses. Copyright © 2022 Lahore Medical And Dental College. All rights reserved.
ABSTRACT
Aim: To determine the long term impact of covid-19 infection on sleep and mental health. Study design: Cross-sectional study Place and duration of study: Department of Psychiatry, Ghulam Mohammad Mahar Medical College Sukkur from 1st April 2021 to 30th September 2021. Methodology: Fifty patients were enrolled after their positivity confirmation of coronavirus-19 through nasal swab test polymerase chain reaction. Categorization was done on the basis of disease severity. HRCT was performed for complete chest examination and grading of covid-19. Other laboratory tests were also done for day to day assessment of patient. Patients after their recovery were asked to follow up after six months of their disease. The demographic, gender, clinical history and clinical record were documented on a well-structured questionnaire. Co-morbidities associated were also recorded. Sleep and mental health were assessed by Pittsburgh sleep quality index. This assessment tool is used to identify sleep disturbances. The scoring techniques use seven sub scores ranging between 0-3. Results: The mean age was 49.56±12.2 years with almost equal males and females. In 66% of the participants of severe group and critical group were suffering from poor sleep quality followed by non severe group. Phobic anxieties were more common in non-severe and severe cases while paranoid ideation was normal in severe cases but at borderline in critical cases. Paranoid ideation was more common in married as well as single patients. Conclusion: Corona virus badly influences normal sleep cycle and also leads towards various mental and psychological disorders.